D7288Brush Biopsy - Transepithelial Sample Collection
2026 Billing Guide
Covers brush biopsy - transepithelial sample collection for pathological evaluation of oral tissue.
What This Code Covers
D7288 covers brush biopsy - transepithelial sample collection. A brush device collects transepithelial cells from a mucosal surface for laboratory analysis. The specimen is sent to a pathology laboratory with appropriate documentation.
Billing Guide
Bill this code when:
- The biopsy procedure described by D7288 is performed
- The tissue type (hard or soft) matches the code description
- A specimen is submitted to pathology with the appropriate requisition
Do not bill this code when:
- The tissue type does not match (hard tissue vs. soft tissue)
- No specimen was actually collected or submitted for analysis
- The procedure is better coded as an excision rather than a biopsy
- The procedure is better described by D7270 (Tooth reimplantation and/or stabilization of accid...)
Insurance and Denial Prevention
Key Payer Rules:
- Surgical procedures may be covered under dental or medical insurance depending on the plan
- Impacted tooth extractions are often covered under both dental and medical plans
- Complex surgical procedures may require prior authorization
- Pathology-related procedures may be better covered under the medical benefit
Common Denials and How to Respond:
- Should be billed to medical - Some oral surgery codes are covered under medical rather than dental benefits. Check both plans.
- Not medically necessary - Submit operative notes, radiographs, and pathology reports to support the surgical indication.
- Complexity level disputed - Document the surgical approach, complications, and any bone removal or tooth sectioning performed.
Claim Submission Checklist
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Explore Related Codes
Codes commonly billed alongside or often confused with this procedure.
Incisional Biopsy of Oral Tissue - Soft
Covers incisional biopsy of oral tissue - soft for pathological evaluation of oral tissue.
Exfoliative Cytological Sample Collection
An oral and maxillofacial surgery procedure covering exfoliative cytological sample collection.
Surgical Repositioning of Teeth
Covers surgical repositioning of teeth to relocate or re-establish a tooth in the arch.
Removal of Impacted Tooth - Completely Bony With Unusual Surgical Complications
Surgical removal of a completely bone-impacted tooth with additional complications such as proximity to nerves, unusual root anatomy, or ankylosis.